Brief BIO
Goals and objectives
I am currently a postdoctoral research fellow in Cardiac Surgery at The Johns Hopkins Hospital between my second and third year of training in general surgery at MedStar Health - Georgetown University/Washington Hospital Center. My long-term goal is to become a surgeon-scientist studying the mechanisms and treatment of neurocognitive injury after cardiothoracic surgery, to develop strategies to optimize surgical outcomes and to develop advancements in surgical technique. My academic training started in preclinical rodent research focused on understanding the neurophysiology of learning and memory. I was fascinated by how much we did not understand about fundamental neurobiology and how this research could be applied to improve the lives of patients with cognitive disabilities. This experience propelled me into pursuing a career in translational research in neuroscience. As an undergraduate, I conducted my research thesis, a project I independently designed, on the mechanisms of insulin signaling dysregulation in a mouse model of Parkinson’s Disease. As a medical student, I was captivated by surgery. As a third-year medical student, in my attempt to meld the two worlds of surgery and science, I was fortunate to be granted a predoctoral Howard Hughes Medical Institute fellowship. Here, I was able to obtain proficiency in large animal training, cryostat brain tissue sectioning, immunohistochemistry, ELISA, neurostimulation, rodent and non-human primate neurosurgery and anesthesia, and electrophysiology analysis. More importantly, this experience taught me the importance of mentorship and the crucial need for support in a scientific career.
As a general surgery resident, I have clinical training and experience in treating patients with cardiovascular surgery, but it wasn’t until I personally felt the crippling effects of cardiovascular disease on neurocognition that I made the decision to dedicate my career to the prevention and treatment of this disease. Currently, my goal is to set the foundation to establishing my long-term research goals as a surgeon-scientist in developing novel therapies of neuroprotection for many patients who have lost cognitive function and functional independence.
Interests
Functional And Restorative Neuroscience
Cardiothoracic Surgery
General Surgery
Hobbies
Travel
Movies and Film
Music
Awards
American Heart Association Postdoctoral Fellowship Award
2024 - 2025
Howard Hughes Medical Institute Medical Fellowship Award
2017 - 2019
Arnold P. Gold Humanism Award
2019
B.S. In Biology With Honors
2012
CURRENT PROJECTS
JOHNS HOPKINS HOSPITAL, NEUROPROTECTION IN HYPOTHERMIC CIRCULATORY ARREST
June 2023 - Present
Mentors:
Jennifer S. Lawton, MD.
–
CHILDRENS NATIONAL HOSPITAL, TRACHEOSTOMY IN CONGENITAL CARDIAC SURGERY
September 2021 - Present
Mentors:
Yves d’Udekem, MD.PhD.
–
JOHNS HOPKINS HOSPITAL, OUTCOMES IN MITRAL VALVE REPAIR
December 2023 - Present
Mentors:
James Gammie, MD.
–
JOHNS HOPKINS HOSPITAL, MULTIPLE ARTERIAL GRAFTING IN CABG/ CABG OUTCOMES IN WOMEN
October 2023 - Present
Mentors:
Jennifer S. Lawton, MD.
–
PAST PROJECTS
MASSACHUSETTS GENERAL HOSPITAL, NEURAL DYNAMICS OF UNCONSCIOUSNESS
September 2017 - May 2019
Mentors:
Emery Brown, MD.PhD.
Non-Human Primates: Yumiko Ishizawa, MD.PhD.
Rodent: Francisco J. Flores, PhD.
–
MASSACHUSETTS GENERAL HOSPITAL, DEEP BRAIN STIMULATION THERAPY IN ALZHEIMERS DISEASE
July 2018 - May 2019
Mentors:
Rudy Tanzi, PhD.
Shaun Patel, PhD.
–
MASSACHUSETTS GENERAL HOSPITAL, EPILEPTIC ZONE DIAGNOSIS UTILIZING STEREOTACTIC DEPTH ELECTRODE PLACEMENT
January 2018 - May 2019
Mentors:
Emad Eskandar, MD.
Sarah Bick, MD.
PRESENTATIONS AND PUBLICATIONS
ARTICLE PUBLICATIONS
Dynamics of Recovery from Anesthesia-induced Unconsciousness Across Primate Neocortex
Patel SR, Ballesteros JJ, Ahmed OJ, Huang P, Briscoe J, Eskandar EN, Ishizawa Y.
Brain. March 2020. PMCID: PMC7868001
–
Structural and Functional Network Dysfunction in Parkinson’s Disease
Herrington, T.M., Briscoe, J.B., Eskandar, E.
Radiology. December 2017
–
Neural signatures of α2-Adrenergic agonist-induced unconsciousness and awakening by antagonist
Ballesteros JJ, Briscoe JB, Ishizawa Y.
Elife. 2020 Aug 28. PMCID: PMC7455241
–
Pain control after thoracic surgery begins in the operating room
Briscoe JB, Caso R.
J Thorac Dis. 2022 Aug. PMCID: PMC9442529.
ORAL PRESENTATIONS
Novel Analgesic Targets for Chronic Pain
Geisinger Commonwealth SOM Summer Research Symposium
Scranton, Pennsylvania, July 29, 2015
–
Modulation of Glucose Signaling by L-DOPA Administration
MBRS-RISE MARC U*STAR at University of Texas San Antonio
San Antonio, Texas, April 20, 2012
–
Auditory Cortical Neurons and Bandwidth Selective Frequency Tuning
University of Oregon Research Symposium. Eugene, Oregon, August 2010
POSTER PRESENTATIONS
The Harsh Reality of Tracheostomy in Congenital Cardiac Surgery
Briscoe JB, Venna A, Mehta R, Domnina Y, Greenlick-Michals H, Desai M, Tongut A, Yerebakan C, d"Udekem Y.
Society of Thoracic Surgery Annual Meeting. 2024 January 27. San Antonio, TX, USA
–
Retrospective Analysis of the Safety and Efficacy of Depth Electrode Placement with and without Robotic Assistance: A Single-Institution Study
Briscoe JB, Mulvaney G, Bick SK, Eskandar E.
Congress of Neurosurgical Surgeons 2018 Annual Meeting [E-Poster]. October, 2018. Houston, TX
–
Modulation of Glucose Signaling by L-DOPA Administration
Briscoe JB, Giuffrida A.
MBRS-RISE MARC U*STAR Symposium. March, 2012. San Antonio, Texas.
PLEASE SEE A COMPLETE LIST OF PUBLISHED WORK IN MY BIBLIOGRAPHY:
HTTPS://WWW.NCBI.NLM.NIH.GOV/MYNCBI/JESSICA.BRISCOE.1/BIBLIOGRAPHY/PUBLIC/
Education
Medstar health - georgetown university/washington hospital center, washington, DC
POSTGRADUATE GENERAL SURGERY TRAINING
2020 - Present
Geisinger Commonwealth school of medicine, scranton
MEDICAL DOCTORATE
2020
Geisinger Commonwealth school of medicine, scranton
MASTER OF BIOMEDICAL SCIENCE
2013
UNIversity of Texas San Antonio, San Antonio
B.S. BIOLOGICAL SCIENCE, NEUROSCIENCE CONCENTRATION WITH HONORS
2012
UNIversity of Texas San Antonio, San Antonio
B.A. PSYCHOLOGY
2012